Based on the acidity difference of phenolic hydroxyl and alcoholic hydroxyl in p-hydroxyphenylethyl alcohol, the betaxolol hydrochloride intermediate was synthesized by selective A.W.Williamson etherification between p-hydroxyphenylethyl alcohol and epichlorohydrin in 18% potassium carbonate-acetone alkalescent solution. Based on the acidity difference of phenolic hydroxyl and alcoholic hydroxyl in p-hydroxyphenylethyl alcohol, the betaxolol hydrochloride intermediate was synthesized by selective A.W.Williamson etherification between p-hydroxyphenylethyl alcohol and epichlorohydrin in 18 % potassium carbonate-acetone alkalescent solution. Tamsulosin Hydrochloride is the hydrochloride salt of tamsulosin, a sulfonamide derivative with adrenergic antagonist activity. Tamsulosin selectivity binds to and blocks the activity of alpha1 adrenoreceptors in the human prostate and bladder neck; blockade of these adrenoceptors can cause smooth muscle in the prostate and bladder neck to relax, resulting in an improvement in urinary flow rate. Search results for 63659-19-8 at Sigma-Aldrich. Compare Products: Select up to 4 products. *Please select more than one item to compare Download Citation | Characterization and Synthesis of A Betaxolol Hydrochloride Intermediate | In this paper, a new method was developed to synthesize betaxolol hydrochloride intermediate (1-[4-(2 Chemical Synthesis (1) Microbiology (7) Special Grade. analytical standard (1) BioChemika (6) certified reference material (3) Microbiology (5) pharmaceutical secondary standard (2) Betaxolol hydrochloride. 1 Product Result | Match Criteria: Description
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